Home » Conditions » PSC (Primary Sclerosing Cholangitis)
Primary sclerosing cholangitis is similar to PBC (primary biliary cholangitis) but it affects the bile ducts inside and outside the liver. It causes the bile ducts to become inflamed, scarred and narrowed which can eventually lead to liver cirrhosis.
It is still unclear what causes PSC, but it is thought to be an immune response to a toxin or infection. PSC has a genetic predisposition, meaning if a family member has or had PSC, you are more likely to have it as well.
Other risk factors of PSC include:
PSC is most commonly diagnosed before any symptoms appear during a routine test for other conditions. Treatment of PSC is more effective when caught earlier.
Other common symptoms of PSC include:
It is important to make an appointment with your nearest GI Alliance gastroenterologist if you have intense itching on much of your body, or if you feel very tired all the time. It is especially important to bring these symptoms up to your doctor if you have a type of inflammatory bowel disease such as ulcerative colitis or Crohn’s disease.
The medical community has not found a cure for PSC. Most of the treatments involve treating the narrowed bile ducts and the symptoms and complications associated with the disease.
Treatments for PSC include:
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